Foto‐Induzierte Ruthenium‐Katalysierte Doppel C(sp <sup>2</sup> )−H/C(sp <sup>3</sup> )−H Funktionalisierungen durch Radikalübertragungen
نویسندگان
چکیده
Abstract Distale C(sp 2 )−H‐ und 3 )−H‐Funktionalisierungen haben sich kürzlich als schrittökonomische Werkzeuge für die molekulare Synthese entwickelt. Obwohl der Aufbau von )−C(sp )‐Bindungen grundlegender Bedeutung ist, hat ihre Bildung durch doppelte )−H/C(sp )−H‐Aktivierung schwierig erwiesen. Durch Kombination Ruthenium‐katalysierten meta ‐C(sp )−H‐Funktionalisierung einen aliphatischen Wasserstoffatomtransfer (HAT)‐Prozess beschreiben wir hier zweifach foto‐induzierte Ruthenium‐vermittelte Radikalübertragungen. Somit wurden )−H‐Arenbindungen distale )−H‐Alkanbindungen einzigen Katalysator aktiviert. Dieser Prozess wurde bei Raumtemperatur unter Bestrahlung mit sichtbarem Licht erreicht – bemerkenswerterweise ohne exogene Photokatalysatoren. Experimentelle rechnerische Studien deckten zugrunde liegenden mechanistischen Schritte auf, ortho ‐C−H‐Aktivierung, Einzelelektronentransfer (SET), 1, n ‐HAT ( =5–7) σ ‐Aktivierung Ruthenium(II)‐Katalysator umfassten.
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2022
ISSN: ['1521-3773', '1433-7851', '0570-0833']
DOI: https://doi.org/10.1002/ange.202205562